Understanding Hepatitis B Antibody Tests
WEB IgG Anti-HBc: A Persistent Marker of Past Infection
The WEB IgG Anti-HBc blood test detects antibodies to the Hepatitis B core antigen (HBc). These antibodies remain positive indefinitely after an individual has been infected with Hepatitis B Virus (HBV), even after the infection has cleared. Therefore, a positive WEB IgG Anti-HBc test result indicates that the person has been previously exposed to HBV.
WEB Anti-HBs: Interpreting Results for Immunity
Negative Result (Less than 5 mIU):
A level of less than 5 mIU indicates that the individual is not immune to Hepatitis B and requires vaccination.
Test and Result Interpretation Action
| Test | Result | Action |
|---|---|---|
| HBsAg | Positive | Possible acute or chronic HBV infection |
| Total Anti-HBc | Positive | Past HBV infection |
| IgM Anti-HBc | Positive | Acute or recent HBV infection |
Screening and Vaccination Recommendations
The table below provides recommendations for screening testing and vaccination based on age and risk factors.
| Age/Risk Factor | Screening | Vaccination |
|---|---|---|
| Children | Birth, 1-2 months, 6-18 months | Yes |
| Adults with risk factors (e.g., healthcare workers, travelers) | Regularly | Yes |
HBc Total Antibody Test: Absence of Exposure
A negative Hepatitis B Core (HBc) Total Antibody test result indicates that the individual has not been exposed to Hepatitis B virus.
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